The ketogenic diet, a diet mainly based on lipids, would have therapeutic virtues for the heart. This is revealed by a study carried out on animals.
- The ketogenic diet would be good for our heart, it would prevent certain heart diseases
- This diet of cutting carbs in favor of fat could even treat heart failure
But since we tell you that fat is life! Researchers from the University of Saint-Louis (United States) have shown that a diet high in fat, as in the ketogenic diet, could prevent certain heart diseases. The results of their study were published on October 26, 2020 in the journal Nature Metabolism.
The contribution of lipids
The ketogenic diet involves drastically reducing the carbohydrate content in your diet to replace it mostly with fat and protein. In mice, severe heart failure was prevented by a ketogenic diet. According to the study by Kyle McCommis, professor of biochemistry and molecular biology at Saint Louis University and lead author of the study, this diet could have a similar effect in humans.
“From high-fat, low-carb diets could be a nutritional therapeutic intervention to treat heart failure”, says Kyle McCommis.
The heart muscle needs a large amount of nutrients to ensure its contractions. To maintain this high capacity, the heart has an adaptive capacity that allows it to be flexible and function even when pathologies such as diabetes or heart failure prevent it from working normally.
Limit heart failure
In mice, a period of fasting has a ketogenic effect. After 24 hours of fasting, the level of glucose in the blood is reduced, and the concentrations of fatty acids and ketone bodies increase. In his study, Kyle McCommis realizes that the MPC (mitochondrial pyruvate carrier) when it is under-expressed in mice, leads to a “remodeling” of its heart, which makes it possible to avoid certain cardiac dysfunctions.
“Interestingly, this heart failure can be prevented, or even reversed, by a “ketogenic” diet, high in fat and low in carbohydrates.says Kyle McCommis. A 24-hour fast in mice, which is also ‘ketogenic’, also resulted in significant improvement in cardiac remodeling“.
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