It has been repeatedly said that taking granules is incompatible with the consumption of mint (including in toothpaste), Coffee, tea, alcohol and tobacco. Absorption of the active ingredient from homeopathic medicines is done, in fact, perlingually, that is to say through the small vessels of the oral mucosa. These substances being astringent, they constrict the veins located under the tongue (vasoconstriction) and therefore hamper the distribution of the drug. In fact, one should only avoid consuming these products when taking the remedies, so as not to reduce their effectiveness. For an optimal effect, it is advisable to respect an interval of half an hour before taking the granules and fifteen minutes after.