The impairment of the coagulation process is clinically manifested by hemorrhages. In 80% of cases, it is a factor VIII or hemophilia A deficiency. In the remaining 20% of cases, the deficiency is factor IX (hemophilia B).
The clinical symptoms are similar in both cases.
Girls, “carriers of the anomaly”, may present with bleeding disorders that must be taken into account in various situations, but the disease never has the same severity in them as in boys.
There are approximately 4,000 people with hemophilia in France. Half of them suffer from a severe form. To promote the management of this disease, the Hemophilia Information Bus invites patients and their relatives to 4 large cities in France.
The Hemophilia Information Bus will soon be on the road to meet people with hemophilia and those around them in order to make them aware of the evolutions related to the disease, to answer questions and to help them improve their daily lives thanks to tools of information and entertainment on board.
At the initiative of Wyeth, in partnership with the Association Française des Hémophiles (AFH), the Information Bus will be stationed in the center of 4 large cities until the end of October:
– Bordeaux, Sunday October 11, 2009
– Rouen, Wednesday October 14, 2009
– Marseille, Sunday October 18, 2009
Diagnostic
Its precocity depends on the degree of hemophilia and it is facilitated by the notion of family heredity.
The biological examination (blood test to measure factor VIII / IX) makes it possible to both define the type (A or B) and the form of hemophilia (severe, mild or moderate).
The severe forms are most often diagnosed at birth with a hematoma that has arisen spontaneously or after minimal trauma.
The moderate forms often appear later when walking, the occasions of trauma then becoming more frequent. Sometimes the pathology is revealed only in adolescence.
In mild forms, the hemorrhages are secondary to a serious injury or to an operative act.
Source: http://www.wyeth-hemophilie.com/
