October 9, 2000 – Two new studies, the first on 93 people with osteoarthritis of the knee, the second on rabbits, strengthen the scientific evidence on the beneficial effect of glucosamine and chondroitin against osteoarthritis.
The first research showed that more than half of the experimental group saw symptoms of osteoarthritis decrease compared to 28% in the placebo group. The experimental group received twice daily 1000 mg of glucosamine hydrochloride, 800 mg of chondroitin sulfate and 152 mg of manganese ascorbate. On the other hand, those with very advanced knee osteoarthritis did not feel any improvement.
The second study, in a group of rabbits that had cartilage removed to simulate osteoarthritis in humans, showed that the arthritic process was slowed down in rabbits receiving the treatment. The best results were obtained with animals given a combination of glucosamine and chondroitin rather than the compounds taken separately. This research is one of the first to document the superior effect of the glucosamine-chondroitin combination, but more studies will be needed to confirm this result.
The research, which may answer all the questions, should begin in October. Indeed, the US National Institutes of Health is preparing to launch a research of $ 10 million among 1,500 people who will receive glucosamine, chondroitin and a combination of the two. The objective of this large study, which has been in preparation for almost two years, is to measure the effect of the products studied on arthritis pain and the process of joint degradation.
After The Boston Globe, September 27, 2000
Das A Jr, Hammad TA. Efficacy of a combination of FCHG49trade mark glucosamine hydrochloride, TRH122trade mark low molecular weight sodium chondroitin sulfate and manganese ascorbate * in the management of knee osteoarthritis. Osteoarthritis Cartilage. 2000 Sep; 8 (5): 343-50.
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