Moderate physical activity would be effective in combating the effects of lupus, an autoimmune disease, according to the results of a study published in the medical journal Frontiers in Physiology. Indeed, exercise would reduce the amount of biomarkers responsible for inflammation. These conclusions were obtained in mice.
Researchers at Ohio State University in the United States conducted a study in mice carrying the lupus to understand the effects of exercise and stress on disease.
They found that 45 minutes of treadmill daily significantly reduced inflammatory damage to rodent kidneys.
Through their experience, they also noticed that the majority (88%) of sedentary guinea pigs suffered severe damage, while only 45% of active mice suffered the same disorders, and that stress increased disease biomarkers.
Results confirmed on humans
To confirm the results of this study, the researchers performed a small-scale experiment. A small group of lupus patients practiced daily tai chi, moderate-intensity physical activity, and weight reduction exercises. stress.
Scientists observed a significant decrease in certain inflammatory biomarkers identified in the rodent experiment. A key step in setting up larger studies.
“We hear from many patients complaining of aches and pains that keep them from getting out of bed in the morning and playing sports,” says lead study author Nicholas Young, rheumatology and immunology researcher at Ohio State Wexner Medical Center. “One of the biggest hurdles to overcome is the idea that activating seems counterintuitive, but movement is actually good for the patient.”
“If we see proven benefits in large groups of people with lupus and can find a suitable standard program, we could almost imagine a prescription for physical activity and reduction in blood pressure. stress“.
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