A study presented at an international congress of reproductive medicine shows that taking ibuprofen before embryo transfer improves the pregnancy rate.
Ibuprofen treatment prescribed just before embryo transfer improves the outcome of IVF. This is the conclusion of a study that has just been presented at the joint conference of the International Federation of Fertility Societies (IFFS) and the American Society for Reproductive Medicine (ASRM) in Boston.
A significantly better pregnancy and implantation rate
This analysis presented by a team of researchers from the Farhat Hached University Hospital in Sousse (Tunisia) focused on 166 patients receiving an IVF cycle with transfer of fresh embryos. These women were divided into two groups. In the first, 90 min before the embryo transfer, the patients were given 200 mg of ibuprofen orally, while in the other, the women were given a placebo. As a result, the pregnancy rate was significantly higher among the women who had received ibuprofen, 34.93% compared to 20.48% of pregnancy among those who had received a placebo. In addition, the embryo implantation rate was also higher, 15.10% against 9.60%. Finally, according to the report of this communication, the rate of miscarriage was also lower in patients who had taken ibuprofen just before the procedure.
New studies to understand the effect of ibuprofen
“To our knowledge, this is the first study to assess the possible consequences of oral ibuprofen before embryo transfer to improve the results of IVF”, specify the Tunisian researchers. However, the authors of this work have not yet succeeded in explaining precisely the mechanism of action of ibuprofen in this indication. They therefore suggest that further studies be carried out to better understand its effect in improving the results of in vitro fertilization.
Source: APM
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