A recent re-evaluation of these drugs by Afssaps showed a risk of adverse effects, in particular neuropsychiatric complications, respiratory depression and a risk of drowsiness.
While some first-generation H1 antihistamine cough medications and fenspiride are still available in pharmacies despite a contraindication in infants under two years of age, others are withdrawn from the market as of March 15.
The list of contraindicated drugs in children under two years of age:
– CALMIXENE, syrup (Novartis Pharma SAS)
– OXOMEMAZINE BIOGARAN 0.33 mg / ml, syrup (Biogaran)
– OXOMEMAZINE BIOGARAN 0.33 mg / ml SS, oral solution sweetened with acesulfame potassium (Biogaran)
– OXOMEMAZINE EG 0.33 mg / ml, syrup (EG Labo)
– OXOMEMAZINE EG 0.33 mg / ml SS, oral solution sweetened with acesulfame potassium (EG Labo)
– OXOMEMAZINE PHR LAB 0.33 mg / ml, syrup (PHR LAB)
– OXOMEMAZINE PHR LAB 0.33 mg / ml SS, oral solution sweetened with acesulfame potassium (PHR LAB)
– OXOMEMAZINE TEVA 0.33 mg / ml, syrup (Teva Santé)
– OXOMEMAZINE TEVA 0.33 mg / ml SS, oral solution sweetened with acesulfame potassium (Teva Santé)
– OXOMEMAZINE WINTHROP 0.33 mg / ml, syrup (Sanofi-Aventis)
– OXOMEMAZINE WINTHROP 0.33 mg / ml SS, oral solution sweetened with acesulfame potassium (Sanofi-Aventis)
– PNEUMOREL 0.2%, syrup (Servier)
– TOPLEXIL 0.33 mg / ml SS, oral solution sweetened with acesulfame potassium (Sanofi-Aventis)
– TOPLEXIL 0.33 mg / ml, syrup (Sanofi-Aventis)
The list of drugs withdrawn from the market
– BRONCALENE INFANTS, syrup (Hepatoum)
– INFANTS HEXAPNEUMINE, syrup (Bouchara Recordati)
The list of drugs contraindicated for infants only in the indication of cough
– THERALENE 4%, oral solution in drops (Erempharma)
– THERALENE 0.05%, syrup (Erempharma)
