Vitiligo is a autoimmune disease during which white spots appear on the skin. These progressive depigmentations are more or less extensive. Although the disease is considered medically “mild”, it has a considerable psychological impact. The wait for treatment is therefore particularly strong because “current solutions such as phototherapy, corticosteroids and inhibitors have limited effectiveness” underlines Dr David Rosmarin, dermatologist at Tufts Medical Center in Boston (United States).
A cream based on ruxolitinib
The latter has just published the results of the clinical trial of a topical cream, which has been shown to be effective in reversing the effects of vitiligo in 50% of patients who have tested it. This two-year study included 157 patients at 30 sites across the United States. “Topical application of ruxolitinib, currently used as an oral treatment for certain blood disorders, resulted in substantial improvement in the symptoms of facial vitiligo in nearly half of the trial participants,” the doctor told Congress World of Dermatology which was held in Milan last weekend.
“The ruxolitinib topical has the potential to change the treatment of vitiligo. Not only is it effective in repigmenting the skin, it also has an excellent safety profile, “added Dr. Rosmarin. The latter hopes to achieve even better results by combining the cream with phototherapy and exposure to the sun. Sun.
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