Researchers have discovered that three proteins prevent the risk of suffering from heart failure after a heart attack.
- Every year, 80,000 people suffer from a myocardial infarction, also called a heart attack.
- Heart attack is the main cause of heart failure, a chronic disease characterized by the inability of the heart to pump blood throughout the body.
- Researchers have identified three proteins which, administered after a heart attack, would prevent the onset of heart failure.
According to health insuranceeach year around 80,000 people have a myocardial infarction called Also heart attack. It can be defined as the destruction of part of the heart muscle. Most of the time, the infarction leaves after-effects because certain heart cells are irreparably destroyed.
Infarction: administration of 3 proteins to prevent heart failure
After a heart attack, some patients may develop heart failure. This chronic disease is due to an inability of the heart to properly fulfill its role of propelling blood in the body. Treatment and a healthy lifestyle can moderate the worsening and reduce episodes of decompensation requiring patient hospitalization.
According to‘Health Insurance, Heart attack is the most common cause of heart failure. Researchers have asked themselves the question of how to limit the risks of heart failure after a myocardial infarction. The results of their work were published in the journal Science Translational Medicine.
Scientists found that administering three proteins after a heart attack could prevent the onset of heart failure. IThey used a technology called “FunSel”, which made it possible to identify these three human proteins among more than 1,000. These are Chrdl1, Fam3c and Fam3b.
Administer one of these proteins after a heart attack
“This is the very first time that potentially curative factors for the heart have been directly identified for their therapeutic potential“, explains Mauro Giacca, one of the authors of the work in a communicated. Laboratory experiments on mice showed that these three proteins would prevent heart damage after a heart attack and thus eliminate the risk of heart failure.
“Any of the three proteins we identified can be administered immediately after a heart attack to minimize heart damage and thus prevent heart failure, develops Mauro Giacca. There has been no significant progress in this area for a long time, so we are very excited about this discovery.“
For the moment, the effectiveness of these three proteins has not yet been tested on humans. “The potential of this therapy is extremely important and could revolutionize treatments for patients at risk of heart failure.specifies Ajay Shah, professor and director of British Heart Foundation Center for Research Excellence at King’s College London. There are no effective preventive therapies for the deterioration of heart tissue following a [infarctus du myocarde]this is therefore a major advance in this area.
