A team of scientists from Nice led by Patrick Collombat has just published the encouraging results of their research on diabetes in the specialized journal Developmental Cell. Their findings could pave the way for new innovative avenues to treat type 1 diabetes, the autoimmune form of this disease that requires people to inject insulin to recover. to regulate blood sugar and supply the cells with glucose.
The researchers therefore studied the different mechanisms at the origin of this disorder in mice genetically modified to artificially induce type 1 diabetes. destruction of cells à ?? producers of insulin, they discovered that other cells were able to produce this hormone. Thus, it would be possible to regenerate pancreatic cells at least three times, by diverting the cells that generate glucose (glucagon) from their primary function.
Scientists are now investigating whether the human pancreas also has this regenerative capacity in order to consider a new anti-diabetes treatment. Indeed, if it were possible to develop drugs allowing pancreatic cells to regenerate, patients would no longer need to do so. insulin shots.
