A skin patch using nanotechnology to turn white fat into brown fat would be effective in treating metabolic disorders like obesity and diabetes, according to the researchers. results of a study published in the medical journal ACS Nano. Conclusions obtained are mice.
Reduce fat 20%
Researchers at Columbia University in the United States have developed a skin patch capable of transforming white fat to brown fat, white fat stores energy, and brown fat stores energy. An effect to fight against obesity and diabetes.
This patch fitted with dozens of microscopic needles makes it possible to deliver a drug in nanoparticles of approximately 250 nanometers (nm) in diameter. The needles, applied to the skin, odorlessly diffuse the drug into the underlying tissue.
Scientists evaluated their test on mice. Applied for 3 days over a total of 4 weeks on fatty areas of guinea pigs, the patch allowed a 20% reduction in fat on the treated side, a lower fasting blood sugar level than that of the mice in the control group. In addition, patch care promotes oxygen consumption by around 20%.
“This patch is a ‘non-invasive’ method that could reduce pockets of fat compared to liposuction. It should not only be used cosmetically, but would be a safer alternative to the treatment of metabolic diseases such asobesity and the diabetes. The next step would be to try the patches on humans and verify their efficacy and effectiveness in clinical trials, ”concludes Zhen Gu, associate associate professor of biomedical engineering at the University of North Carolina.
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