Very effective vaccines for several months. This is the conclusion of a new publication by the Epi-Phare group, which combines Health Insurance (Cnam) and the Medicines Agency (ANSM), confirming “the major impact of vaccination” against covid.
This study is based on data from the National Health Data System (SNDS) of more than 22 million people. It shows that the vaccines against Covid-19 (Pfizer, Moderna and AstraZeneca) reduce the risk of hospitalization and death in people over 50 by 90%. Better, it suggests that the vaccines would be just as effective against the Delta variant.
9 times less risk of being hospitalized
To conduct this research, professionals from the Epi-Phare group compared the data of 11 million vaccinated people aged over 50 with those of 11 million unvaccinated people in the same age group. This comparison took place from December 27, 2020, the date of the start of vaccination in France, to July 20.
Result ? At the end of the “complete vaccination” scheme, i.e. 15 days after the second dose, the researchers observed that vaccinated people were nine times less likely to be hospitalized for Covid-19 than unvaccinated people of the same age. .
At least five months of efficacy after the first dose
But for how long ? According to this study, the effectiveness of vaccination does not seem to decrease over time. The risk of a severe form was in fact reduced until at least five months after the second dose. It will be necessary to continue this study over time to determine after how many months the vaccine loses its effectiveness.
It also remains to be seen whether vaccines, effective against severe forms, are also effective against the risk of infection and transmission of covid.
Also effective against the Delta variant?
Last unknown for researchers: the effectiveness of vaccines against the Delta variant, now dominant in France. The Epi-Phare study has already observed that the reduction in the risk of hospitalization for Covid-19 persists at the start of the appearance of the Delta variant in France, in the summer of 2021. But these results will have to be updated ” to assess the evolution of efficacy over a longer period” and to “better characterize the effects of the Delta variant”, already warns the Epi-Phare group in a press release.
- Impact of vaccination on the risk of severe forms of Covid-19, Epi-Phare reportOctober 11, 2021
- Vaccination is more than 90% effective in reducing severe forms of Covid-19 in people over 50 in France. Joint press release from the Ansm, the Epi-Phare group and the Health Insurance, October 11, 2021
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