In France, one in six women and one in eight men on average are subject to more or less violent chronic headaches. Those migrainescan be very annoying on a daily basis. If there is no miracle treatment Against this debilitating pathology, the causes are also quite difficult to identify. An international consortium in which Inserm researchers participated in particular set out to compare 29 genomic studies corresponding to no less than 118,000 genetic profiles, including 23,000 from people with migraine.
In the review Nature Genetics which relays the progress of this work, we learn that scientists have put their finger on five new genetic regions that could be involved in triggering migraines. These areas would be located near other genetic regions close to the cerebral cortex. The “understanding of migraine susceptibility [est] still modest, but […] may ultimately contribute to the development of new treatments “, according to the authors, cited by Santé log.
While more studies are needed to understand the exact function of the genes identified, the researchers believe that the sum of some of them could disrupt the regulation of tissues and nerve cells, triggering migraine symptoms.
