Many are still unaware of it, but cardiovascular diseases are responsible for one in three deaths among women, ahead of cancers (including breast cancer). Deaths partly caused by ignorance of the symptoms of infarction, which are different in women, and therefore by too late treatment.
“Measuring the protein troponin in the blood is the current gold standard for diagnosing a heart attack. However, the levels of troponin released by the heart vary between men and women, with age and other issues of health” underlines the British heart foundation.
In a study, published in The Lancet , researchers from Switzerland and the UK analyzed data from more than 420,000 patients across Europe who had suffered a heart attack. They were thus able to verify that the management of the disease is less precise in women, which favors the under-treatment of patients. “Using a machine learning algorithm, we were able to develop a novel artificial intelligence-based risk score that accounts for sex-related differences in the baseline risk profile and improves mortality prediction in both sexes” says Dr. Florian Wenzl of the Center for Molecular Medicine at the University of Zürich (Switzerland), lead author of the study.
“Our study heralds the era of artificial intelligence in the treatment of heart attacks,” he says.
Source : Sex-specific evaluation and redevelopment of the GRACE score in non-ST-segment elevation acute coronary syndromes in populations from the UK and Switzerland: a multinational analysis with external cohort validationThe Lancet, August 2022
