Drinking three cups of coffee a day may have a protective effect against the onset of several cardiometabolic diseases.
- Regular coffee consumption, especially at moderate levels, is associated with a lower risk of new-onset cardiometabolic multimorbidity, i.e. the coexistence of two or more cardiometabolic diseases.
- The “ideal” dose of coffee to consume would be “three cups of coffee, or 200 to 300 mg of caffeine per day.”
- “In total, 80 to 97 metabolites were identified as being associated with both coffee, tea or caffeine consumption and the incidence of cardiometabolic conditions.”
Coffee is often blamed for cardiovascular problems. Observational research has suggested inverse associations between coffee, tea, and caffeine consumption and the risks of cardiometabolic diseases, such as type 2 diabetes, coronary heart disease, and stroke. “However, their links with cardiometabolic multimorbidity, a growing public health problem, and the associated biological markers are unknown,” reported researchers from Soochow University in Suzhou, China.
Consume “200 to 300 mg of caffeine per day” to be protected from cardiometabolic diseases
Thus, they conducted a study to determine the ideal “dose” of coffee to consume in order to reduce the risks of cardiometabolic pathologies. For the purposes of the work, the team used data (medical records, care, hospitalizations, death registers) from the UK Biobank. In total, 172,315 people aged 37 to 73 years consuming coffee and 188,091 drinking coffee and tea were included in the research. The participants, whose metabolites (intermediate organic compounds or from metabolism) were measured, did not have any disease at recruitment and enrollment. Cardiometabolic diseases were defined as the coexistence of at least two of the following conditions: type 2 diabetes, coronary heart disease and stroke.
Compared with non-consumers or consumers of less than 100 mg of caffeine per day, consumers of moderate amounts of coffee or caffeine had the lowest risk of developing coronary heart disease. According to the results, published in the journal The Journal of Clinical Endocrinology & Metabolismregular consumption of coffee or caffeine, especially at a moderate level, is associated with a lower risk of new cardiometabolic diseases and could play an important role in almost all transition phases of the development of cardiometabolic pathologies. In detail, the “ideal” dose would be “three cups of coffee, or 200 to 300 mg of caffeine per day,” specified Chaofu Kelead author of the study.
Diabetes, stroke: 80 to 97 metabolites linked to coffee consumption
“A total of 80 to 97 metabolites, such as lipid components of very low density lipoproteins, histidine and acetyl glycoproteins, were identified as being associated with both coffee, tea or caffeine consumption and the incidence of cardiometabolic conditions,” can be read in the work. According to the team, further research is needed to validate the metabolic biomarkers involved that underlie the link between coffee, tea and caffeine consumption and cardiometabolic diseases.
