Hope for one out of two men who suffer from baldness from 55 years old. It comes from American dermatologists who have just published an encouraging study in the journal Science Advances. Columbia University researchers demonstrate that two drugs already approved by the US Food and Drug Administration could solve the alopecia problem(loss of hair).
The two promising molecules, ruxolitinib and tofacitinib, are treatments currently used to treat certain cancers but also rheumatoid arthritis (inflammatory joint disease). The drugs were tested on mice and human hair follicles transplanted into mice. They would be able to restart the growth of hair follicles by blocking certain immune cells responsible for hair loss.
In the experiment of the American researchers, these drugs were applied in the form of a cream to their hair for five days. Ten days later, the mice’s hair grew back. The growth of human hair follicles grafted onto the rodents was also accelerated under the effect of the treatment.
Clinical tests to be carried out
“Very few components have shown such a powerful and rapid action” on hair regrowth, concluded Dr. Cristiano, author of the study. Further work is awaited to determine whether these treatments are truly effective against baldness, the final stage of alopecia.
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