The polyarthritis rheumatoid is an inflammatory joint disease that affects nearly 0.3% of the French population, according to the National Institute of Health (Inserm). Painful joints swell and deform, which can lead to functional disability. The few existing treatments can stabilize the disease, but a new study carried out by Swiss researchers would make it possible to cure it completely.
Scientists have managed to treat mice with rheumatoid arthritis by injecting them with a product that binds to the protein in inflammatory tissue. The drug only targets areas of pain, thus limiting side effects. “This allows us to concentrate an active substance where the evil is and the concentration in the rest of the body is minimal”, explain Teresa Hemmerle, one of the authors of the study.
Mice with rheumatoid arthritis who received this treatment were found to be completely cured. These promising animal results pave the way for clinical trials in humans with arthritis. According to the researchers, these experiments will begin next year.
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