Does ibuprofen increase the risk of cardiovascular disease when prescribed for a long time and in high doses? This is the answer that the EMA must provide after an evaluation of this drug. The review of this treatment began on June 9, 2014 at the request of the UK Health Agency.
THE’ibuprofen belongs to a class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is present in medicines used to treat pain, inflammation and fever.
The usual dose for adults and children over 12 years old is 200 to 400 mg, 3 or 4 times a day as needed. In this context, the EMA does not question the safety of the product. And the majority of patients don’t have to worry. On the other hand, she wants to assess the risks
In 2013, the PRAC had already reviewed the available data on diclofenac, a nonsteroidal anti-inflammatory drug and issued recommendations to minimize their risks. cardiovascularfor daily treatments greater than 2400 mg per day. Indeed the results of a published analysis based on several clinical trials have suggested that the cardiovascular risk with diclofenac and high dose ibuprofen (2400 mg) may be similar to the known risks with COX inhibitors. -2, like Vioxx withdrawn from the market because it is too dangerous (another drug in the NSAID class).
The PRAC will also assess the interaction between ibuprofen and aspirin, even in low doses and taken to reduce heart risks and stroke. Based on the results of this research, it will provide healthcare professionals with new recommendations regarding ibuprofen and its use.
Even if the exams are not completed, patients should not stop their treatments without medical advice.
