The use of perhexiline against pancreatic cancer could be effective.
- A drug used in cardiology could cure pancreatic cancer.
- Scientists have found that perhexiline, in combination with chemotherapy, induces complete tumor removal.
- Pancreatic cancer is one of the most aggressive and treatment-resistant cancers available.
Scientists recently made a promising discovery in the fight against pancreatic cancer. According work published in the journal iSciencepreclinical trials have shown encouraging results from the use of perhexiline, a drug currently used in Australia and New Zealand to treat a specific cardiac condition.
Impressive results in preclinical trials
Researchers conducted experiments on xenograft mice and found that combining perhexilin with chemotherapy led to complete removal of the tumor responsible for pancreatic cancer.
A synergy between perhexiline and chemotherapy
According to scientists, perhexiline and chemotherapy act synergistically to induce an anti-tumor effect. They speculate that this combination causes energetic and oxidative stress within the tumor, leading to its complete destruction. However, the exact mechanisms of this beneficial action have yet to be determined by further research.
The results of preclinical trials on the use of perhexiline in the treatment of pancreatic cancer are encouraging. This discovery offers new perspectives in the fight against this difficult to treat disease. It also raises hopes of improving survival rates and quality of life for patients with pancreatic cancer.
Pancreatic cancer: a therapeutic challenge
Pancreatic cancer is one of the most aggressive and treatment-resistant cancers available. It is often diagnosed at an advanced stage, which greatly limits treatment options. Current treatments, such as chemotherapy, have limited efficacy, which makes the discovery of new therapeutic approaches all the more crucial.
