Fluconazole and itraconazole are used to treat vaginal infections. In pregnant women, they can cause fetal malformations.
Some medications are not compatible with pregnancy. In International Journal of Gynecology & Obstetricsresearchers show that oral treatments to treat vaginal infections are not recommended for pregnant women because they can have consequences on the health of the fetus.
Vaginal infections, common during pregnancy
Vaginal yeast infections due to fungi do not spare pregnant women, on the contrary, they produce more sex hormones, which creates a favorable ground for these infections. Most cases are treated with creams, ointments and other gels applied locally, but for some women this treatment is not enough. Doctors usually prescribe oral tablets in these cases, such as fluconazole or itraconazole.
Risks to the heart and eyesight
In this research, scientists gathered data from eight studies conducted on the effects of these drugs on pregnant women and fetuses. They find that these tablets do not increase the risk of birth defects, but that fluconazole is associated with a higher risk of defects in the heart or one of the limbs. Consumption of itraconazole is linked to an increased risk of eye or vision problems.
Identify risky drugs
Since 2017 and the Depakine affair, drugs toxic to the fetus have included a pictogram on their packaging to better identify them. For all treatments, the leaflet is the reference text for knowing the side effects or risks for pregnant women. If in doubt, it is necessary to consult a doctor or pharmacist.
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