According to an American study, the HMB, an over -the -counter supplement used by bodybuilders and bodybuilding followers to increase their muscle mass, could also protect from Alzheimer’s disease.
- HMB is an additional supplement to increase muscle mass.
- A study on mice has shown that this supplement reduces amyloid plates, responsible for Alzheimer’s disease.
- Other research must be carried out to verify that these results are proven in humans.
HMB (or calcium β-hydroxy-β-methylbutyrate), very popular with bodybuilders, would not only act on muscles, but also on the brain. According to a study by the Rush University (Chicago), this supplement which frequently completes the diet of bodybuilding enthusiasts could protect memory and prevent Alzheimer’s disease.
Dementia: HMB would reduce amyloid plates
Rush University scientists have discovered that β-hydroxy-β-methylbutyrate calcium (HMB) could help protect memory, reduce amyloid plates and prevent the development of Alzheimer’s disease. They arrived at this conclusion after studying mice suffering from this neurodegenerative pathology. The results have shown that HMB successfully reduces plates and also increases neural growth factors thus protecting memory.
“Our study revealed that after oral absorption, HMB is entering the brain to increase beneficial proteins (neurotrophe factors Editor’s note), restore neural connections and improve memory and learning in mice with a pathology of a pathology of Alzheimer’s type, like plates and tangles “said in a press release The main author of the works, Dr Kalipada Pahan, professor of neurology, biochemistry and pharmacology at the Rush Medical College. These results suggest that the supplement could play an important role in the protection and restoration of cognitive functions altered by Alzheimer’s disease.
Hmba :: possible advance in the fight against Alzheimer’s disease
The work authors have also noticed that the Hmba stimulates in the brain a nuclear hormonal receiver, called Pparαregulating the transport of fatty acids. By activating it, it promotes the production of neuronal growth factors. This helps protect and regenerate neurons, essential for memory and learning as well as for dementia prevention.
“If the results observed on the mice having taken Hmba are reproduced in patients with Alzheimer’s disease, this would open a promising path of treatment for this devastating neurodegenerative disease “concluded the author of the study published in Cell Postponement.
